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KRAS Antibody

Catalog Number:OM283067
OM283067
Discount Price
OM283067-100ul
1~2 Week
100ul
OM283067-50ul
50ul
OM283067-20ul
20ul
1~2 Week
Product Profile
Product Name KRAS Antibody
Antibody Type Primary Antibodies
Antigen Alias KRAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2, NS, CFC2
Product description KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.1) Turbiner, J., (er) Mod. Pathol. (2008) In press.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KRAS.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
KRAS antibody can be used for detection of KRAS by ELISA at 1:62500. KRAS antibody can be used for detection of KRAS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity DrosophilaHumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol KRAS
Alternative Names KRAS
C-K-RAS
K-RAS2A
K-RAS2B
K-RAS4A
K-RAS4B
KI-RAS
KRAS1
KRAS2
NS3
RASK2
NS
CFC2
Molecular Weight(MW) 22 kDa
Database Links
Entrez Gene 3845
Protein Accession NP_203524
Application

Application

Antibody used in WB on candida albicans Ras1P at: 1:5000.

Application

Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Positive Control 1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Application Notes KRAS antibody can be used for detection of KRAS by ELISA at 1:62500. KRAS antibody can be used for detection of KRAS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store KRAS antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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