Application
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.| Product Name | KREMEN1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KREMEN1, FLJ31863, KREMEM1, KREMEN, KRM1 |
| Product description | KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.1) Mao, B., (2002) Nature 417 (6889), 664-667. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KREMEN1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| KREMEN1 antibody can be used for detection of KREMEN1 by ELISA at 1:62500. KREMEN1 antibody can be used for detection of KREMEN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KREMEN1 |
|---|---|
| Alternative Names | KREMEN1 FLJ31863 KREMEM1 KREMEN KRM1 |
| Molecular Weight(MW) | 50 kDa |
| Entrez Gene | 83999 |
|---|---|
| Protein Accession | NP_001034659 |
Application
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1219 - MCF7 Cell Lysate |
|---|---|
| Application Notes | KREMEN1 antibody can be used for detection of KREMEN1 by ELISA at 1:62500. KREMEN1 antibody can be used for detection of KREMEN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store KREMEN1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
