Application
Western blot analysis in A375 cell line lysates (35ug/lane).| Product Name | KRT75 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Keratin, type II cytoskeletal 75, Cytokeratin-75, CK-75, Keratin-6 hair follicle, hK6hf, Keratin-75, K75, Type II keratin-K6hf, Type-II keratin Kb18, KRT75, K6HF, KB18 |
| Product description | This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).1) Sperling, L.C., et al. J. Cutan. Pathol. 37(2):243-248(2010) |
| Immunogen | This KRT75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-92 amino acids from the N-terminal region of human KRT75. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KRT75 |
|---|---|
| Alternative Names | Keratin type II cytoskeletal 75 Cytokeratin-75 CK-75 Keratin-6 hair follicle hK6hf Keratin-75 K75 Type II keratin-K6hf Type-II keratin Kb18 KRT75 K6HF KB18 |
| Molecular Weight(MW) | 60 kDa |
Application
Western blot analysis in A375 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
