This gene encodes L-2-hydroxyglutarate dehydrogenase, a
FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to
alpha-ketoglutarate in a variety of mammalian tissues. Mutations in
this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal
recessive neurometabolic disorder resulting in moderate to severe
mental retardation.1) Short, A.D., et al. Vet. Rec. 167(12):455-457(2010)
Immunogen
This L2HGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH.
Western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.