Application
Antibody used in WB on Human Brain at 0.2-1 ug/ml.| Product Name | L3MBTL Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | L3MBTL, DKFZp586P1522, FLJ41181, H-L(3)MBT, KIAA0681, L3MBTL1, dJ138B7.3, L3MBTL, ZC2HC3 |
| Product description | L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.1) Min, J., (2007) Nat. Struct. Mol. Biol. 14 (12), 1229-1230. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human L3MBTL. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| L3MBTL antibody can be used for detection of L3MBTL by ELISA at 1:1562500. L3MBTL antibody can be used for detection of L3MBTL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | L3MBTL1 |
|---|---|
| Alternative Names | L3MBTL DKFZp586P1522 FLJ41181 H-L(3)MBT KIAA0681 L3MBTL1 dJ138B7.3 L3MBTL ZC2HC3 |
| Molecular Weight(MW) | 86 kDa |
Application
Antibody used in WB on Human Brain at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate |
|---|---|
| Application Notes | L3MBTL antibody can be used for detection of L3MBTL by ELISA at 1:1562500. L3MBTL antibody can be used for detection of L3MBTL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store L3MBTL antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
