Application
Immunohistochemistry of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 5 μg/mL.Application
Immunofluorescence of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 20 μg/mL.Application
Western blot analysis of LAMTOR3 in human brain tissue lysate with LAMTOR3 antibody at (A) 1 and (B) 2 μg/ml| Product Name | LAMTOR3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LAMTOR3 Antibody: MP1, MAPBP, MAPKSP1, PRO0633, MAP2K1IP1, Ragulator3, PRO2783, Ragulator complex protein LAMTOR3, MEK-binding partner 1, Mp1 |
| Product description | The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).1) Wunderlich W, Fialka I, Teis D, et al. A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold MP1 on a late endosomal/lysosomal compartment. J. Cell Biol. 2001; 152:765-76. |
| Immunogen | LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LAMTOR3 |
|---|---|
| Alternative Names | LAMTOR3 Antibody: MP1 MAPBP MAPKSP1 PRO0633 MAP2K1IP1 Ragulator3 PRO2783 Ragulator complex protein LAMTOR3 MEK-binding partner 1 Mp1 |
| Molecular Weight(MW) | Predicted: 14 kDa Observed: 13 kDa |
| Sequence Similarities | 2) Cat. No. 10-301 - Human Brain Tissue Slide |
| Tissue Specificity | LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist; this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins. |
Application
Immunohistochemistry of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 5 μg/mL.
Application
Immunofluorescence of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 20 μg/mL.
Application
Western blot analysis of LAMTOR3 in human brain tissue lysate with LAMTOR3 antibody at (A) 1 and (B) 2 μg/ml| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | LAMTOR3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | LAMTOR3 Antibody is supplied in PBS containing 0.02% sodium azide. |
