LASS5 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When it is overexpressed in cells it is involved in the production of sphingolipids containing mainly only one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.1) Kitatani, K., (2006) J. Biol. Chem. 281 (48), 36793-36802.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LASS5.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
LASS5 antibody can be used for detection of LASS5 by ELISA at 1:12500. LASS5 antibody can be used for detection of LASS5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
LASS5 antibody can be used for detection of LASS5 by ELISA at 1:12500. LASS5 antibody can be used for detection of LASS5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store LASS5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.