Leukocyte immunoglobulin-like receptor subfamily A member 5, CD85 antigen-like family member F, Immunoglobulin-like transcript 11, ILT-11, Leukocyte immunoglobulin-like receptor 9, LIR-9, CD85f, LILRA5, ILT11, LILRB7, LIR9
Product description
The protein encoded by this gene is a member of the
leukocyte immunoglobulin-like receptor (LIR) family. LIR family
members are known to have activating and inibitory functions in
leukocytes. Crosslink of this receptor protein on the surface of
monocytes has been shown to induce calcium flux and secretion of
several proinflammatory cytokines, which suggests the roles of this
protein in triggering innate immune responses. This gene is one of
the leukocyte receptor genes that form a gene cluster on the
chromosomal region 19q13.4. Four alternatively spliced transcript
variants encoding distinct isoforms have been described. [provided
by RefSeq].1) Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Immunogen
This LILRA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human LILRA5.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.