Application
Western Blot at 1:500-1:2000 dilution Lane 1: Daudi whole cell lysate Lane 2: Raji whole cell lysate Lane 3: Ramos whole cell lysate Lane 4: SH-SY5Y whole cell lysate Lysates/proteins at 20 ug per lane.| Product Name | LILRB1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Leukocyte immunoglobulin-like receptor subfamily B member 1, LIR-1, Leukocyte immunoglobulin-like receptor 1, CD85 antigen-like family member J, Immunoglobulin-like transcript 2, ILT-2, Monocyte/macrophage immunoglobulin-like receptor 7, MIR-7, CD85j, LILR |
| Product description | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
| Immunogen | This LILRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the Central region of human LILRB1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:500-1:2000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LILRB1 |
|---|---|
| Alternative Names | Leukocyte immunoglobulin-like receptor subfamily B member 1 LIR-1 Leukocyte immunoglobulin-like receptor 1 CD85 antigen-like family member J Immunoglobulin-like transcript 2 ILT-2 Monocyte/macrophage immunoglobulin-like receptor 7 MIR-7 CD85j LILR |
| Molecular Weight(MW) | 71 kDa |
Application
Western Blot at 1:500-1:2000 dilution Lane 1: Daudi whole cell lysate Lane 2: Raji whole cell lysate Lane 3: Ramos whole cell lysate Lane 4: SH-SY5Y whole cell lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:500-1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
