Application
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).| Product Name | LILRB4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Leukocyte immunoglobulin-like receptor subfamily B member 4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, ILT-3, Leukocyte immunoglobulin-like receptor 5, LIR-5, Monocyte inhibitory receptor HM18, CD85k, LILRB4, ILT3, LIR5 |
| Product description | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.1) Davila, S., et al. Genes Immun. 11(3):232-238(2010) |
| Immunogen | This LILRB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human LILRB4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LILRB4 |
|---|---|
| Alternative Names | Leukocyte immunoglobulin-like receptor subfamily B member 4 CD85 antigen-like family member K Immunoglobulin-like transcript 3 ILT-3 Leukocyte immunoglobulin-like receptor 5 LIR-5 Monocyte inhibitory receptor HM18 CD85k LILRB4 ILT3 LIR5 |
| Molecular Weight(MW) | 49 kDa |
Application
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
