Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Product Name | LMBR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LMBR1, ACHP, C7orf2, DIF14, FLJ11665, PPD2, TPT, ZRS |
| Product description | LMBR1 is a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of LMBR1 gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if LMBR1 gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Wang, Z.Q., (2007) Biochem. Biophys. Res. Commun. 355 (2), 312-317. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LMBR1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| LMBR1 antibody can be used for detection of LMBR1 by ELISA at 1:1562500. LMBR1 antibody can be used for detection of LMBR1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LMBR1 |
|---|---|
| Alternative Names | LMBR1 ACHP C7orf2 DIF14 FLJ11665 PPD2 TPT ZRS |
| Molecular Weight(MW) | 55 kDa |
Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | LMBR1 antibody can be used for detection of LMBR1 by ELISA at 1:1562500. LMBR1 antibody can be used for detection of LMBR1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store LMBR1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
