Application
Western blot analysis of anti-Lmx1a Pab in HL60 cell line lysates (35ug/lane).| Product Name | Lmx1a Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 11, LMX-11, LIM/homeobox protein LMX1A, Lmx1a |
| Product description | Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.1) Mangale,V.S., Science 319 (5861), 304-309 (2008) |
| Immunogen | This Lmx1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human Lmx1a. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | Lmx1a |
|---|---|
| Alternative Names | LIM homeobox transcription factor 1-alpha LIM/homeobox protein 11 LMX-11 LIM/homeobox protein LMX1A Lmx1a |
| Molecular Weight(MW) | 43 kDa |
Application
Western blot analysis of anti-Lmx1a Pab in HL60 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
