Application
Western blot analysis of extract from JK and Raji cells using LPAM-1 (Integrin & CD49d).| Product Name | LPAM 1 (Integrin a4, CD49d) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IA4, CD49D, CTNNB, OK/SW-cl.35, PRO2286, IA4, MGC90518, ITGA4 |
| Product description | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.1) Iida J., Meijne A. M. L., Oegema T. R. Jr., Yednock T. A., Kovach N. L., Furcht L. T., McCarthy J. B. J. Biol. Chem. 273:5955-5962 (1998) Liu S., Thomas S. M., Woodside D. G., Rose D. M., Kiosses W. B., Pfaff M., Ginsberg M. H. Nature 402:676-681 (1999) |
| Immunogen | LPAM-1 (Integrin a4, CD49d) antibody was raised against a peptide sequence around aa.1024~1028 (Y-I-N-S-K) derived from Human LPAM-1 (Integrin α4, CD49d). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITGA4 |
|---|---|
| Alternative Names | IA4 CD49D CTNNB OK/SW-cl.35 PRO2286 IA4 MGC90518 ITGA4 |
| Molecular Weight(MW) | 70, 140, 180 kDa |
| Tissue Specificity | This antibody detects endogenous level of total LPAM-1(Integrin α4, CD49d) protein. |
| Entrez Gene | 3676 |
|---|---|
| Protein Accession | NP_000876.3 |
Application
Western blot analysis of extract from JK and Raji cells using LPAM-1 (Integrin & CD49d).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
