This gene encodes a member of the latrophilin subfamily of
G-protein coupled receptors (GPCR). Latrophilins may function in
both cell adhesion and signal transduction. In experiments with
non-human species, endogenous proteolytic cleavage within a
cysteine-rich GPS (G-protein-coupled-receptor proteolysis site)
domain resulted in two subunits (a large extracellular N-terminal
cell adhesion subunit and a subunit with substantial similarity to
the secretin/calcitonin family of GPCRs) being non-covalently bound
at the cell membrane.1) Arcos-Burgos, M., et al. Mol. Psychiatry 15(11):1053-1066(2010)
Immunogen
This LPHN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the N-terminal region of human LPHN3.
Western blot analysis in mouse spleen tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.