Application
Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 μg/mL.| Product Name | LY6K Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LY6K Antibody: CT97, ly-6K, HSJ001348, CO16, Lymphocyte antigen 6K, Ly-6K |
| Product description | LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.1) de Nooij-van Dalen AG, van Dongen GA, Smeets SJ, et al. Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma. Int. J. Cancer 2003; 103:768-74. |
| Immunogen | LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human LY6K. The immunogen is located within the first 50 amino acids of LY6K. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| LY6K antibody can be used for detection of LY6K by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LY6K |
|---|---|
| Alternative Names | LY6K Antibody: CT97 ly-6K HSJ001348 CO16 Lymphocyte antigen 6K Ly-6K |
| Tissue Specificity | Multiple isoforms of LY6K are known to exist. |
Application
Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | LY6K antibody can be used for detection of LY6K by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | LY6K antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | LY6K Antibody is supplied in PBS containing 0.02% sodium azide. |
