Application
Immunofluorescence of LYRM1 in rat liver tissue with LYRM1 antibody at 20 μg/mL.Application
Immunohistochemistry of LYRM1 in rat liver tissue with LYRM1 antibody at 5 μg/mL.Application
Western blot analysis of LYRM1 in human liver tissue lysate with LYRM1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | LYRM1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LYRM1 Antibody: A211C6.1, LYR motif-containing protein 1 |
| Product description | LYRM1 Antibody: LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.1) Qiu J, Ni YH, Gong HX, et al. Identification of differentially expressed genes in omental adipose tissues of obese patients by suppression subtractive hybridization. Biochem. Biophys. Res. Comm.2007; 352:469-78. |
| Immunogen | LYRM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human LYRM1. The immunogen is located within the first 50 amino acids of LYRM1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LYRM1 |
|---|---|
| Alternative Names | LYRM1 Antibody: A211C6.1 LYR motif-containing protein 1 |
Application
Immunofluorescence of LYRM1 in rat liver tissue with LYRM1 antibody at 20 μg/mL.
Application
Immunohistochemistry of LYRM1 in rat liver tissue with LYRM1 antibody at 5 μg/mL.
Application
Western blot analysis of LYRM1 in human liver tissue lysate with LYRM1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1304 - Human Liver Tissue Lysate |
|---|---|
| Application Notes | LYRM1 antibody can be used for detection of LYRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | LYRM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | LYRM1 Antibody is supplied in PBS containing 0.02% sodium azide. |
