Mitotic spindle assembly checkpoint protein MAD1, Mitotic arrest deficient 1-like protein 1, MAD1-like protein 1, Mitotic checkpoint MAD1 protein homolog, HsMAD1, hMAD1, Tax-binding protein 181, MAD1L1, MAD1, TXBP181
Product description
MAD1L1 is a component of the mitotic spindle-assembly
checkpoint that prevents the onset of anaphase until all chromosome
are properly aligned at the metaphase plate. MAD1L1 functions as a
homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell
cycle control and tumor suppression. Three transcript variants
encoding the same protein have been found for this gene. [provided
by RefSeq].1) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Immunogen
This MAD1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-151 amino acids from the N-terminal region of human MAD1L1.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.