Application
Antibody is used in Western blot to detect MAGEA6 in A549 lysate.| Product Name | MAGEA6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MAGEA6 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.1) Tatsumi, T., et al., Clin. Cancer Res. 9(3):947-954 (2003). |
| Immunogen | This MAGEA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human MAGEA6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Symbol | MAGEA6 |
|---|---|
| Alternative Names | Melanoma-associated antigen 6 Cancer/testis antigen 16 CT16 MAGE-6 antigen MAGE3B antigen MAGEA6 MAGE6 |
| Molecular Weight(MW) | 35 kDa |
Application
Antibody is used in Western blot to detect MAGEA6 in A549 lysate.| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
