Application
Western blot analysis of MATN1 in mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | MATN1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MATN1 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.1) Pei M, Luo J, and Chen Q. Enhancing and maintaining matrilins. Osteoarthritis Cartilage2008; 16:1110-7. |
| Immunogen | MATN1 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human MATN1. The immunogen is located within amino acids 120 - 170 of MATN1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MATN1 antibody can be used for detection of MATN1 by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MATN1 |
|---|---|
| Alternative Names | MATN1 Antibody: CMP CRTM CMP Cartilage matrix protein Matrilin-1 |
Application
Western blot analysis of MATN1 in mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1404 - Mouse Liver Tissue Lysate |
|---|---|
| Application Notes | MATN1 antibody can be used for detection of MATN1 by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MATN1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MATN1 Antibody is supplied in PBS containing 0.02% sodium azide. |
