Application
Western blot analysis of MATN2 in 3T3 cell lysate with MATN2 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | MATN2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MATN2 Antibody: Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.1) Pei M, Luo J, and Chen Q. Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins. Osteoarthritis Cartilage2008; 16:1110-7. |
| Immunogen | MATN2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human MATN2. The immunogen is located within amino acids 820 - 870 of MATN2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MATN2 antibody can be used for detection of MATN2 by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MATN2 |
|---|---|
| Alternative Names | MATN2 Antibody: Matrilin-2 |
| Molecular Weight(MW) | Predicted: 102 kDa Observed: 105 kDa |
Application
Western blot analysis of MATN2 in 3T3 cell lysate with MATN2 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1282 - 3T3 (NIH) Cell Lysate |
|---|---|
| Application Notes | MATN2 antibody can be used for detection of MATN2 by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MATN2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MATN2 Antibody is supplied in PBS containing 0.02% sodium azide. |
