Application
Immunohistochemistry of MATN4 in mouse brain tissue with MATN4 antibody at 2.5 μg/mL.Application
Immunofluorescence of MATN4 in mouse brain tissue with MATN4 antibody at 20 μg/mL.Application
Western blot analysis of MATN4 in rat brain tissue lysate with MATN4 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | MATN4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MATN4 Antibody: Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. Members of the matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices such as embryonic kidney, lung, bone, cartilage and nervous system. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation. MATN4 could serve as an odontoblast differentiation marker, e.g. in odontoblast stem cell research.1) Pei M, Luo J, and Chen Q. Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins. Osteoarthritis Cartilage2008; 16:1110-7. |
| Immunogen | MATN4 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human MATN4. The immunogen is located within amino acids 110 - 160 of MATN4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| MATN4 antibody can be used for detection of MATN4 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MATN4 |
|---|---|
| Alternative Names | MATN4 Antibody: Matrilin-4 |
Application
Immunohistochemistry of MATN4 in mouse brain tissue with MATN4 antibody at 2.5 μg/mL.
Application
Immunofluorescence of MATN4 in mouse brain tissue with MATN4 antibody at 20 μg/mL.
Application
Western blot analysis of MATN4 in rat brain tissue lysate with MATN4 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | MATN4 antibody can be used for detection of MATN4 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MATN4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MATN4 Antibody is supplied in PBS containing 0.02% sodium azide. |
