This gene is a candidate colorectal tumor suppressor gene
that is thought to negatively regulate cell cycle progression. The
orthologous gene in the mouse expresses a phosphoprotein associated
with the plasma membrane and membrane organelles, and
overexpression of the mouse protein inhibits entry into S phase.
Multiple transcript variants encoding different isoforms have been
found for this gene.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This MCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-501 amino acids from the Central region of human MCC.
Western blot analysis in U937 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.