Application
Antibody used in WB on Human Raji at 1.25 ug/ml.| Product Name | MDS1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.1) Fears, S., et al., (1996) Proc. Natl. Acad. Sci. U.S.A. 93 (4), 1642-1647. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MDS1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MDS1 antibody can be used for detection of MDS1 by ELISA at 1:312500. MDS1 antibody can be used for detection of MDS1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MDS1 |
|---|---|
| Alternative Names | MDS1 PRDM3 MDS1-EVI1 |
| Molecular Weight(MW) | 19 kDa |
Application
Antibody used in WB on Human Raji at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1207 - Raji Cell Lysate |
|---|---|
| Application Notes | MDS1 antibody can be used for detection of MDS1 by ELISA at 1:312500. MDS1 antibody can be used for detection of MDS1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store MDS1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
