Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.1) Seong H. -A., Gil M., Kim K. -T., Kim S. -J., Ha H. Biochem. J. 361:597-604 (2002) Vulsteke V., Beullens M., Boudrez A., Keppens S., Van Eynde A., Rider M. H., Stalmans W., Bollen M. J. Biol. Chem. 279:8642-8647 (2004)
Immunogen
MELK antibody was raised against a peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.