Application
Confocal immunofluorescent analysis of MESDC2 Antibody with 293 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
MESDC2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.Application
Western blot analysis of lysates from K562, mouse NIH/3T3 cell line (from left to right), using MESDC2 Antibody at 1:1000 at each lane.| Product Name | MESDC2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.1) Murrills, R.J., et al. J. Cell. Biochem. 108(5):1066-1075(2009) |
| Immunogen | This MESDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human MESDC2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IFIHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MESDC2 |
|---|---|
| Alternative Names | LDLR chaperone MESD Mesoderm development candidate 2 Mesoderm development protein Renal carcinoma antigen NY-REN-61 MESDC2 KIAA0081 MESD |
| Molecular Weight(MW) | 26 kDa |
Application
Confocal immunofluorescent analysis of MESDC2 Antibody with 293 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
MESDC2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application
Western blot analysis of lysates from K562, mouse NIH/3T3 cell line (from left to right), using MESDC2 Antibody at 1:1000 at each lane.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
