There are believed to be over 100 different
glycosyltransferases involved in the synthesis of protein-bound and
lipid-bound oligosaccharides. The enzyme encoded by this gene
transfers a GlcNAc residue to the beta-linked mannose of the
trimannosyl core of N-linked oligosaccharides and produces a
bisecting GlcNAc. Multiple alternatively spliced variants, encoding
the same protein, have been identified.1) Benson, V., et al. Int. Immunol. 22(3):167-177(2010)
Immunogen
This MGAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-454 amino acids from the C-terminal region of human MGAT3.
Beta-1 4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III GNT-III GlcNAc-T III N-acetylglucosaminyltransferase III MGAT3 GGNT3
Molecular Weight(MW)
61 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Mouse
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.