MIST is a member of the SLP76 family of adaptors (see
LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the
regulation of immunoreceptor signaling, including PLC-gamma (PLCG1;
MIM 172420)-mediated B cell antigen receptor (BCR) signaling and
FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell
degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al.,
2000, 2001 [PubMed 10744659] [PubMed 11463797]).1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.