MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22;q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.1) Wei, J., (2008) Cancer Cell 13 (6), 483-495.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLLT3.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
MLLT3 antibody can be used for detection of MLLT3 by ELISA at 1:1562500. MLLT3 antibody can be used for detection of MLLT3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.
Positive Control
1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes
MLLT3 antibody can be used for detection of MLLT3 by ELISA at 1:1562500. MLLT3 antibody can be used for detection of MLLT3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MLLT3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.