MMP13 is a Metallopeptidase M10A type protease. Metalloproteinase 13/Collagenase 3 (MMP13) was originally identified in breast carcinoma and has since been documented in a variety of tumors including chondrosarcomas, basal cell carcinoma, and malignant melanoma. In addition it has been detected in inflammatory diseases such as atherosclerosis, in wound healing, and in destructive joint diseases such OA and RA. MMP13 degrades the native helix of several types of fibrillar collagen, and extracellular matrix proteins in vitro.
Immunogen
MMP13 antibody was raised against a peptide located in the N-Terminal domain of MMP13 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC
MMP13 antibody can be used in Western Blot starting at 1 - 10 μg/mL, immunohistochemistry starting at 5 μg/mL, immunocytochemistry starting at 0.1 - 1 μg/mL, and immunoprecipitation starting at 1 - 10 μg/mL
Immunohistochemistry staining of MMP13 in breast carcinoma tissue using MMP13 Antibody.
Application Notes
MMP13 antibody can be used in Western Blot starting at 1 - 10 μg/mL, immunohistochemistry starting at 5 μg/mL, immunocytochemistry starting at 0.1 - 1 μg/mL, and immunoprecipitation starting at 1 - 10 μg/mL
Additional Information
Form
Liquid
Storage Instructions
Store MMP13 antibody at 4 ˚C for short term applications. For long term storage, aliquot and -20 ˚C.