Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of the protein encoded by this gene has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19). Multiple transcript variants encoding distict isoforms have been identified for this gene.1) Sadowski, T., et al., (2003) Mol. Biol. Cell 14 (11), 4569-4580.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP19.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
MMP19 antibody can be used for detection of MMP19 by ELISA at 1:1562500. MMP19 antibody can be used for detection of MMP19 by western blot at 5.0-10.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human HepG2 at 5.0-10.0 ug/ml.
Application
Antibody used in IHC on Human at: 1:100.
Application
Antibody used in IHC on Human urinary bladder.
Application
Antibody used in IHC on Human Liver.
Positive Control
1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes
MMP19 antibody can be used for detection of MMP19 by ELISA at 1:1562500. MMP19 antibody can be used for detection of MMP19 by western blot at 5.0-10.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MMP19 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt