Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. This protein is expressed in human
epidermis and it has a role in cellular proliferation as well as
migration and adhesion to type I collagen. Multiple transcript
variants encoding distict isoforms have been identified for this
gene.1) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Immunogen
This MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human MMP19.
Western blot analysis of lysate from human placenta tissue lysate, using MMP19 Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.