Application
Immunohistochemistry of MMP9 in human lung tissue with MMP9 antibody at 2.5 μg/mL.Application
Immunofluorescence of MMP9 in human lung tissue with MMP9 antibody at 5 μg/mL.Application
Western blot analysis of MMP9 in mouse lung tissue lysate with MMP9 antibody at 1 μg/ml.| Product Name | MMP9 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMP9 Antibody : GELB, CLG4B, MMP-9, MANDP2, Matrix metalloproteinase-9, 92 kDa gelatinase |
| Product description | The matrix metalloproteinase (MMP) family are a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases (1). MMP9 degrades type IV and V collagens (2) and studies suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow (3) and plays a role in tumor-associated tissue remodeling (4).1) Iyer RP, Patterson NL, Fields GB, et al. The history of matrix metalloproteinases: milestones, myths, and misperceptions. Am. J. Heart Circ. Physiol 2012; 303:H919-30. |
| Immunogen | MMP9 antibody was raised against a 16 amino acid peptide near the center of human MMP9. The immunogen is located within amino acids 260 - 310 of MMP9 . |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| WB:1:500~1:2000 IF:1:100~1:500 IHC-P:1:50~1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MMP9 |
|---|---|
| Alternative Names | MMP9 Antibody : GELB CLG4B MMP-9 MANDP2 Matrix metalloproteinase-9 92 kDa gelatinase |
| Molecular Weight(MW) | Predicted: 76 kDa Observed: 73kDa |
| Sequence Similarities | 2) Cat. No. 10-101 - Human Lung Tissue Slide |
| Tissue Specificity | MMP9 antibody is human, mouse and rat reactive. At least three isoforms of MMP9 are known to exist; this antibody only recognizes the two longest isoforms. |
Application
Immunohistochemistry of MMP9 in human lung tissue with MMP9 antibody at 2.5 μg/mL.
Application
Immunofluorescence of MMP9 in human lung tissue with MMP9 antibody at 5 μg/mL.
Application
Western blot analysis of MMP9 in mouse lung tissue lysate with MMP9 antibody at 1 μg/ml.| Positive Control | 1) Cat. No. 1402 - Mouse Lung Tissue Lysate |
|---|---|
| Application Notes | WB:1:500~1:2000 IF:1:100~1:500 IHC-P:1:50~1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | MMP9 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | MMP9 Antibody is supplied in PBS containing 0.02% sodium azide. |
