Molybdenum cofactor biosynthesis protein 1, Cell migration-inducing gene 11 protein, Molybdenum cofactor synthesis-step 1 protein A-B, Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein A, Cyclic pyranopterin monophosphate
Product description
Molybdenum cofactor biosynthesis is a conserved pathway
leading to the biological activation of molybdenum. The protein
encoded by this gene is involved in this pathway. This gene was
originally thought to produce a bicistronic mRNA with the potential
to produce two proteins (MOCS1A and MOCS1B) from adjacent open
reading frames. However, only the first open reading frame (MOCS1A)
has been found to encode a protein from the putative bicistronic
mRNA, whereas additional splice variants, whose full-length natures
have yet to be determined, are likely to produce a fusion between
the two open reading frames. This gene is defective in patients
with molybdenum cofactor deficiency, type A. A related pseudogene
has been identified on chromosome 16.1) Sass, J.O., et al. Brain Dev. (2009) In press :
Immunogen
This MOCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human MOCS1.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.