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Acvr1 Antibody

Catalog Number:OM285011
OM285011
Discount Price
OM285011-100ul
1~2 Week
100ul
OM285011-50ul
50ul
OM285011-20ul
20ul
1~2 Week
Product Profile
Product Name Acvr1 Antibody
Antibody Type Primary Antibodies
Antigen Alias Activin receptor type-1, Activin receptor type I, ACTR-I, Serine/threonine-protein kinase receptor R1, SKR1, TGF-B superfamily receptor type I, TSR-I, TSK-7L, Acvr1, Acvrlk2, Tgfb1
Product description On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.1) Luo, J., et al. J. Biol. Chem. 285(38):29588-29598(2010)
Immunogen This Mouse Acvr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the Central region of mouse Acvr1.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Acvr1
Alternative Names Activin receptor type-1
Activin receptor type I
ACTR-I
Serine/threonine-protein kinase receptor R1
SKR1
TGF-B superfamily receptor type I
TSR-I
TSK-7L
Acvr1
Acvrlk2
Tgfb1
Molecular Weight(MW) 57 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Bovine
Database Links
Entrez Gene 11477
Protein Accession P37172
Application

Application

Mouse Acvr1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in mouse bladder tissue lysates (35ug/lane).

Application

Western blot analysis of Acvr1 using rabbit polyclonal Mouse Acvr1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Acvr1 gene.

Application

Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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