Application
Western blot analysis in mouse lung tissue lysates (35ug/lane).| Product Name | Cbx5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Chromobox protein homolog 5, Heterochromatin protein 1 homolog alpha, HP1 alpha, Cbx5, Hp1a |
| Product description | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).1) Sun, Y., et al. Biophys. J. 99(4):1274-1283(2010) |
| Immunogen | This Mouse Cbx5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of mouse Cbx5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Cbx5 |
|---|---|
| Alternative Names | Chromobox protein homolog 5 Heterochromatin protein 1 homolog alpha HP1 alpha Cbx5 Hp1a |
| Molecular Weight(MW) | 22 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Human |
Application
Western blot analysis in mouse lung tissue lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
