Application
Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mdetected the Mouse Cdk14 protein (arrow).| Product Name | Cdk14 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cyclin-dependent kinase 14, Cell division protein kinase 14, Serine/threonine-protein kinase PFTAIRE-1, Cdk14, Kiaa0834, Pftk1 |
| Product description | Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).1) Quina, L.A., et al. J. Neurosci. 29(45):14309-14322(2009) |
| Immunogen | This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Cdk14 |
|---|---|
| Alternative Names | Cyclin-dependent kinase 14 Cell division protein kinase 14 Serine/threonine-protein kinase PFTAIRE-1 Cdk14 Kiaa0834 Pftk1 |
| Molecular Weight(MW) | 53 kDa |
Application
Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mdetected the Mouse Cdk14 protein (arrow).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
