Application
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstratedetected the Dcc protein (arrow).| Product Name | Dcc Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Netrin receptor DCC, Tumor suppressor protein DCC, Dcc |
| Product description | Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene. |
| Immunogen | This Mouse Dcc antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1391-1417 amino acids from the C-terminal region of mouse Dcc. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Dcc |
|---|---|
| Alternative Names | Netrin receptor DCC Tumor suppressor protein DCC Dcc |
| Molecular Weight(MW) | 158 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rat |
Application
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstratedetected the Dcc protein (arrow).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
