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Dnmt3L Antibody

Catalog Number:OM285076
OM285076
Discount Price
OM285076-100ul
1~2 Week
100ul
OM285076-50ul
50ul
OM285076-20ul
20ul
1~2 Week
Product Profile
Product Name Dnmt3L Antibody
Antibody Type Primary Antibodies
Antigen Alias DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
Product description mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.1) Okazaki, Y., et al., Nature 420(6915):563-573 (2002).
Immunogen This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
For WB starting dilution is: 1:1000:
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Gene Symbol Dnmt3l
Alternative Names DNA (cytosine-5)-methyltransferase 3-like
Dnmt3l
Molecular Weight(MW) 48 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Rat
Database Links
Entrez Gene 54427
Protein Accession Q9CWR8
Application

Application

Western blot analysis of Mouse Dnmt3L Antibody in Hela cell line lysates (35ug/lane)

Application

Western blot analysis in mouse liver tissue lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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