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Fyn Antibody

Catalog Number:OM285096
OM285096
Discount Price
OM285096-100ul
1~2 Week
100ul
OM285096-50ul
50ul
OM285096-20ul
20ul
1~2 Week
Product Profile
Product Name Fyn Antibody
Antibody Type Primary Antibodies
Antigen Alias Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, p59-Fyn, Fyn
Product description Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.1) Garcia-Roman, J., et al. Biochem. Biophys. Res. Commun. 401(2):262-267(2010)
Immunogen This Mouse Fyn antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-535 amino acids from the C-terminal region of mouse Fyn.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
For WB starting dilution is: 1:1000:
Species Reactivity Mouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Fyn
Alternative Names Tyrosine-protein kinase Fyn
Proto-oncogene c-Fyn
p59-Fyn
Fyn
Molecular Weight(MW) 61 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Bovine
Database Links
Entrez Gene 14360
Protein Accession P39688
Application

Application

Western blot analysis of Fyn using rabbit polyclonal Mouse Fyn Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Fyn gene.

Application

Western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstratedetected the Fyn protein (arrow).
Application Notes For WB starting dilution is: 1:1000:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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