Homeobox protein Hox-A10, Homeobox protein Hox-18, Hoxa10, Hox-18, Hoxa-10
Product description
In vertebrates, the genes encoding the class of
transcription factors called homeobox genes are found in clusters
named A, B, C, and D on four separate chromosomes. Expression of
these proteins is spatially and temporally regulated during
embryonic development. This gene is part of a cluster on chromosome
6 and encodes a DNA-binding transcription factor that may regulate
gene expression, morphogenesis, and differentiation. More
specifically, it may function in fertility, embryo viability, and
regulation of hematopoietic lineage commitment. Alternatively
spliced transcript variants encoding different isoforms have been
described.1) Gordon, J.A., et al. Mol. Cell. Biol. 30(14):3531-3541(2010)
Immunogen
This Mouse Hoxa10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of mouse Hoxa10.
Western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the detected the Mouse Hoxa10 protein (arrow).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.