The protein encoded by this gene is a member of the
ros/insulin receptor family of tyrosine kinases. Tyrosine-specific
phosphorylation of proteins is a key to the control of diverse
pathways leading to cell growth and differentiation. Four
alternatively spliced transcript variants encoding different
isoforms have been described for this gene. These transcripts are
expressed in a tissue-specific manner in lymphocytes, brain and
neuroblastoma cells, and the encoded isoforms exhibit different
subcellular localization. The lymphocyte and brain specific
variants initiate translation at non-AUG (CUG) start codons.1) Li, J., et al. J. Biol. Chem. 283(49):34260-34272(2008)
Immunogen
This Mouse Ltk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 795-822 amino acids from the C-terminal region of mouse Ltk.
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstratedetected the Ltk protein (arrow).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.