Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.1) Zhong, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(11):4372-4377(2009)
Immunogen
This Mouse Map4k2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-459 amino acids from the Central region of mouse Map4k2.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.