Application
Western blot analysis in MCF-7 cell line lysates (35ug/lane).| Product Name | Mapk8 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, Mapk8, Jnk1, Prkm8 |
| Product description | Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity).1) Sherrin, T., et al. J. Neurosci. 30(40):13348-13361(2010) |
| Immunogen | This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Mapk8 |
|---|---|
| Alternative Names | Mitogen-activated protein kinase 8 MAP kinase 8 MAPK 8 Stress-activated protein kinase JNK1 c-Jun N-terminal kinase 1 Mapk8 Jnk1 Prkm8 |
| Molecular Weight(MW) | 44 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rat |
Application
Western blot analysis in MCF-7 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
