Serine/threonine kinase. Mediates mitotic entry and maintenance. Maintains the correct equilibrium between cyclin B1-CDK1 and protein phosphatase 2A (PP2A) by promoting the inactivation of PP2A. Phosphorylates histone protein in vitro. May be involved in megakaryocyte differentiation (By similarity).1) Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
Immunogen
This Mouse Mastl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-589 amino acids from the Central region of mouse Mastl.
Western blot analysis in mouse liver tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.