Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, Nod1, Card4
Product description
Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens (By similarity).1) Moreno, L., et al. Br. J. Pharmacol. 160(8):1997-2007(2010)
Immunogen
This Mouse Nod1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-584 amino acids from the Central region of mouse Nod1.
Western Blot at 1:1000 dilution + mouse spleen lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.