Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.1) Bawa-Khalfe, T., et al. J. Biol. Chem. 285(33):25859-25866(2010)
Immunogen
This Mouse Senp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-289 amino acids from the Central region of mouse Senp1.
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.