This gene encodes a serine/threonine protein kinase that
plays an important role in cellular stress response. This kinase
activates certain potassium, sodium, and chloride channels,
suggesting an involvement in the regulation of processes such as
cell survival, neuronal excitability, and renal sodium excretion.
This enzyme is activated by protein phosphorylation and degraded
via the ubiquitination and proteasome pathway. Multiple transcript
variants encoding different isoforms have been found for this gene.
A pseudogene of this gene was identified on chromosome 12.1) Gao, D., et al. Mol. Cell 39(5):797-808(2010)
Immunogen
This Mouse Sgk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of mouse Sgk1.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.