Application
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).| Product Name | Sik2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Serine/threonine-protein kinase SIK2, Salt-inducible kinase 2, SIK-2, Serine/threonine-protein kinase SNF1-like kinase 2, Sik2, Snf1lk2 |
| Product description | Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.1) Trivedi, C.M., et al. Dev. Cell 19(3):450-459(2010) |
| Immunogen | This Mouse Sik2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-633 amino acids from the Central region of mouse Sik2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Sik2 |
|---|---|
| Alternative Names | Serine/threonine-protein kinase SIK2 Salt-inducible kinase 2 SIK-2 Serine/threonine-protein kinase SNF1-like kinase 2 Sik2 Snf1lk2 |
| Molecular Weight(MW) | 104 kDa |
Application
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
