Application
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).| Product Name | Sin3a Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a, Transcriptional corepressor Sin3a, Sin3a, Kiaa4126 |
| Product description | Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.1) Baltus, G.A., et al. J. Biol. Chem. 284(11):6998-7006(2009) |
| Immunogen | This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Sin3a |
|---|---|
| Alternative Names | Paired amphipathic helix protein Sin3a Histone deacetylase complex subunit Sin3a Transcriptional corepressor Sin3a Sin3a Kiaa4126 |
| Molecular Weight(MW) | 145 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Human |
Application
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
