Application
Western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the detected the Mouse Slc5a8 protein (arrow).| Product Name | Slc5a8 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Sodium-coupled monocarboxylate transporter 1, Electrogenic sodium monocarboxylate cotransporter, Solute carrier family 5 member 8, Slc5a8 {ECO:0000312|MGI:MGI:2384916} |
| Product description | Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.1) Borthakur, A., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (4), G928-G934 (2010) : |
| Immunogen | This Mouse Slc5a8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-574 amino acids from the C-terminal region of mouse Slc5a8. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Slc5a8 |
|---|---|
| Alternative Names | Sodium-coupled monocarboxylate transporter 1 Electrogenic sodium monocarboxylate cotransporter Solute carrier family 5 member 8 Slc5a8 {ECO:0000312|MGI:MGI:2384916} |
| Molecular Weight(MW) | 67 kDa |
Application
Western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the detected the Mouse Slc5a8 protein (arrow).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
